Drinking alcohol with this medication can increase https://ecosoberhouse.com/article/naltrexone-side-effects-uses-and-risks/ the risk of these side effects. However, it’s essential to acknowledge that not all patients experience the same results. Some may not see significant changes or may even encounter side effects such as vivid dreams, insomnia, or nausea. Individuals with psoriasis, a chronic autoimmune skin condition characterized by red, scaly patches, may find relief with LDN due to its immunomodulatory properties. Eczema, a condition causing itchy and inflamed skin, could also potentially benefit from LDN’s anti-inflammatory effects. Furthermore, LDN may help manage dermatitis, an inflammatory skin condition that leads to redness, itching, and sometimes blistering.
Dr. Jolene Brighten
Patients are encouraged to maintain open communication with their doctors and report any changes in symptoms or quality of life. Keeping a journal documenting symptomatology can aid in this process, providing valuable insights into the treatment’s effectiveness and any common side effects experienced. Since low-dose naltrexone operates on the immune system, even subtle alterations in dosage or frequency can yield significant impacts on the therapeutic outcome. Thus, consistent follow-ups are essential to fine-tune the low-dose naltrexone regimen for optimal results. Perhaps the most evidence to date for off-label use of low-dose naltrexone is fibromyalgia, as noted by Dr. Manasa Irwin in a recent AFP letter to the editor.
Who Is LDN Best For? And Who Should Avoid It?
Talk with your healthcare provider about how to get and administer naloxone. Tell your healthcare provider if you have any of these side effects that bother you. But if you or your loved one needs comprehensive alcohol or opioid addiction treatment, look no further than Granite Recovery Centers in NH. Through structured medication-assisted treatment, we can ensure your recovery is safe and customized to you and your needs. Prescriptions for naltrexone are usually in higher doses for addiction treatment (50 mg or more per day). Varying dosages affect the body differently, emphasizing the need to work with a doctor who understands LDN.
Low-Dose Naltrexone for Women’s Health: Benefits for Hormones, Autoimmunity, and Chronic Pain

Your doctor may decide not to treat you with this medication or change some of the other medicines you take. People with kidney disease or liver disease may need to speak with their doctor before starting LDN. Those who are pregnant or breastfeeding should also speak with their doctor before starting this medication.

- It is unclear if any groups are progressing on this front (though the medication is referenced in a 2013 US patent application filing—US 13/799,287).
- Despite ongoing scientific efforts, there’s not enough clinical data about its effectiveness.
- There is evidence that increasing endogenous endorphin levels can improve insulin control 50.
- To catch any potential issues early, practitioners may recommend regular liver function tests every 6 to 12 months, as well as ongoing tracking of sleep patterns and mood.
- This “opioid rebound” effect could have multiple impacts on health and quality of life, including enhanced endogenous analgesia and repression of critical immune factors 40.
It will not Twelve-step program produce any opioid-like effects or cause mental or physical dependence. It will not prevent you from becoming impaired while drinking alcohol or using opioids. For example, with opioid pain relievers, combining LDN with drugs like Ultram (tramadol) and OxyContin (oxycodone) may cause withdrawal symptoms.
Autoimmune Conditions
- This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally.
- Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.
- However, we must be open to the possibility that the unique clinical effects possible with the low dosage could also present new health risks.
They are most commonly used to treat panic disorder and severe anxiety. Note that opioids might show up where you don’t necessarily expect them to. For example, some cough medications contain opioids (codeine or hydrocodone). Additionally, even some diarrhea medicines like loperamide (the generic name for Imodium) are technically an opioid. Insurance won’t cover LDN since it is an off-label use of the drug naltrexone.

